Directionality of change in obsessive compulsive disorder (OCD) and suicidal ideation over six years in a naturalistic clinical sample

摘要: Abstract Background Obsessive compulsive disorder (OCD) is associated with elevated suicide risk, but the directionality of association between OCD severity and suicidal ideation has not been established, which was goal this study. Methods Participants (n = 325) were adults either a current or past diagnosis Diagnostic Statistical Manual Mental Disorders, 4th Edition (DSM-IV) who assessed annually for symptom six years. Cross-lagged panel analyses statistically compared unidirectional bidirectional models over time. Serious suicide-related adverse events reported. Results The best-fitting most parsimonious model included paths predicting from severity, vice versa. These results confirmed by comparing cross-lagged constrained equal to freely estimated model. Higher in given year higher subsequent year. Five reported throughout duration study, including two deaths three attempts. Limitations study relied on single-item, annual measure adults, substantial variability missing data increased later observations Discussion predicted next severity. In contrast, did predict next-year sample. Thus, rather than waiting resolve, clinicians should consider providing empirically supported treatments OCD.