Dehydroepiandrosterone Sulfate Treatment of Mice Modulates Infection with Schistosoma mansoni
作者： Padraic G. Fallon , Emma J. Richardson , Frances M. Jones , David W. Dunne
DOI: 10.1128/CDLI.5.2.251-253.1998
关键词:
摘要: Female mice treated with dehydroepiandrosterone sulfate early during infection were partially protected (P < 0.05–0.005) from Schistosoma mansoni infection. Hormone treatment did not modify parasite-specific cellular or humoral responses. Serum levels and testosterone negatively correlated, r = −0.621 −0.653, respectively, schistosome worm burden. The partial resistance to in sulfate-treated female may be due the known antischistosomular activity of testosterone.
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