Protein O‐Mannosylation in Metazoan Organisms
作者： Vladislav M. Panin , Lance Wells
DOI: 10.1002/0471140864.PS1212S75
关键词:
摘要: Protein O-mannosylation is a special type of glycosylation that plays prominent roles in metazoans, affecting development and physiology the nervous system muscles. A major biological effect involves regulation α-dystroglycan, membrane glycoprotein mediating cell–extracellular matrix interactions. Genetic defects result loss ligand-binding activity α-dystroglycan cause congenital muscular dystrophies termed dystroglycanopathies. Recent progress mass spectrometry vitro analyses has shed new light on mechanism glycosylation; however, this underlain by complex genetic molecular elements remain poorly understood. evolutionarily conserved yet pathway simplified more amenable to invertebrate organisms, indicating genetically tractable vivo models could facilitate research area. This unit describes recent methodological strategies for studying protein using approaches. Curr. Protoc. Sci. 75:12.12.1-12.12.29. © 2014 John Wiley & Sons, Inc. Keywords: O-glycosylation; O-mannose; congenital dystrophy; dystroglycan; Drosophila ; mass
sci-hub.se 参考文章(76)
Leann M. Mikesh, Beatrix Ueberheide, An Chi, Joshua J. Coon, John E.P. Syka, Jeffrey Shabanowitz, Donald F. Hunt, The utility of ETD mass spectrometry in proteomic analysis. Biochimica et Biophysica Acta. ,vol. 1764, pp. 1811- 1822 ,(2006) , 10.1016/J.BBAPAP.2006.10.003
Theresa Martinez, Danielle Pace, Lowell Brady, Mary Gerhart, Alain Balland, Characterization of a novel modification on IgG2 light chain. Evidence for the presence of O-linked mannosylation. Journal of Chromatography A. ,vol. 1156, pp. 183- 187 ,(2007) , 10.1016/J.CHROMA.2007.04.050
Jenny Jiao, Hailong Zhang, Vernon N. Reinhold, High performance IT-MSn sequencing of glycans International Journal of Mass Spectrometry. ,vol. 303, pp. 109- 117 ,(2011) , 10.1016/J.IJMS.2011.01.016
Andrea H. Brand, Armen S. Manoukian, Norbert Perrimon, Ectopic expression in Drosophila. Methods in Cell Biology. ,vol. 44, pp. 635- 654 ,(1994) , 10.1016/S0091-679X(08)60936-X
T Krusius, J Finne, R K Margolis, R U Margolis, Identification of an O-glycosidic mannose-linked sialylated tetrasaccharide and keratan sulfate oligosaccharides in the chondroitin sulfate proteoglycan of brain. Journal of Biological Chemistry. ,vol. 261, pp. 8237- 8242 ,(1986) , 10.1016/S0021-9258(19)83901-7
J. Finne, T. Krusius, R.K. Margolis, R.U. Margolis, Novel mannitol-containing oligosaccharides obtained by mild alkaline borohydride treatment of a chondroitin sulfate proteoglycan from brain. Journal of Biological Chemistry. ,vol. 254, pp. 10295- 10300 ,(1979) , 10.1016/S0021-9258(19)86708-X
Kazuhiro Kobayashi, Yutaka Nakahori, Masashi Miyake, Kiichiro Matsumura, Eri Kondo-Iida, Yoshiko Nomura, Masaya Segawa, Mieko Yoshioka, Kayoko Saito, Makiko Osawa, Kenzo Hamano, Youichi Sakakihara, Ikuya Nonaka, Yasuo Nakagome, Ichiro Kanazawa, Yusuke Nakamura, Katsushi Tokunaga, Tatsushi Toda, An ancient retrotransposal insertion causes Fukuyama-type congenital muscular dystrophy Nature. ,vol. 394, pp. 388- 392 ,(1998) , 10.1038/28653
Aruto Yoshida, Kazuhiro Kobayashi, Hiroshi Manya, Kiyomi Taniguchi, Hiroki Kano, Mamoru Mizuno, Toshiyuki Inazu, Hideyo Mitsuhashi, Seiichiro Takahashi, Makoto Takeuchi, Ralf Herrmann, Volker Straub, Beril Talim, Thomas Voit, Haluk Topaloglu, Tatsushi Toda, Tamao Endo, Muscular dystrophy and neuronal migration disorder caused by mutations in a glycosyltransferase, POMGnT1. Developmental Cell. ,vol. 1, pp. 717- 724 ,(2001) , 10.1016/S1534-5807(01)00070-3
Christina Bleckmann, Hildegard Geyer, Annika Lieberoth, Frauke Splittstoesser, Yan Liu, Ten Feizi, Melitta Schachner, Ralf Kleene, Vernon Reinhold, Rudolf Geyer, O-glycosylation pattern of CD24 from mouse brain Biological Chemistry. ,vol. 390, pp. 627- 645 ,(2009) , 10.1515/BC.2009.044
Hiroshi Manya, Takehiro Suzuki, Keiko Akasaka-Manya, Hide-Ki Ishida, Mamoru Mizuno, Yasushi Suzuki, Toshiyuki Inazu, Naoshi Dohmae, Tamao Endo, Regulation of Mammalian Protein O-Mannosylation PREFERENTIAL AMINO ACID SEQUENCE FOR O-MANNOSE MODIFICATION Journal of Biological Chemistry. ,vol. 282, pp. 20200- 20206 ,(2007) , 10.1074/JBC.M702369200