Method for suppressing the growth of normal and cancer cells

作者: Francis W. Ruscetti , Larry Ross Ellingsworth

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摘要: Transforming Growth Factor-b (TGF-b) enhances the growth-inhibiting activity of tumor necrosis factor (TNF) or interferon-a (IFN-a) on immune cells and hematopoietic progenitor cells, as well cancer cells. Thus, combinations TGF-b with TNF IFN-a are effec­tive for suppressing cell pro­genitor growth, thus useful treating (e.g., lymphomas, leukemias, myelomas, adeno­carcinomas, etc.), autoimmune chronic inflammatory diseases rheumatoid arthritis, osteoarthritis, myasthenia gravis, lupus erythematosus, uveitis, etc.) hyperproliferative psoriasis vulgaris), organ transplant rejection, protecting from lethal effects chemotherapy radiotherapy.

参考文章(1)
Anita Bauer Roberts, Michael Benjamin Sporn, Repair of tissue in animals ,(1983)