Endothelial cell specifically binding peptides

作者: Joseph Su , Gene Liau , Steingrimur Stefansson

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摘要: The present invention relates to peptides that specifically bind endothelial cells. can be incorporated into gene delivery vector particles and also direct therapeutic agents, including proteins such as growth factors cytokines well small molecules. particles, peptides, or molecules used for the treatment of cancer cardiovascular diseases ischemic heart disease, peripheral limb vein graft stenosis restenosis.

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Stuart A Nicklin, Steve J White, Sarah J Watkins, Robert E Hawkins, Andrew H Baker, None, Selective targeting of gene transfer to vascular endothelial cells by use of peptides isolated by phage display Circulation. ,vol. 102, pp. 231- 237 ,(2000) , 10.1161/01.CIR.102.2.231
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