Osteopromotion for cranioplasty. An experimental study in rats using a membrane technique.

摘要: ✓ Various techniques for treatment of large cranial defects have been reported, but the use alloplastic materials still seems to predominate. The authors applied and explored a new approach bone repair which appears promising, even in less osteogenic environments such as adult calvaria. Seventy-two Sprague-Dawley rats each received bilateral 8-mm trephine temporoparietal area; this defect size precludes spontaneous osseous healing during lifetime animal. Five surgical procedures, employing various alternatives biologically inert expanded polytetrafluoroethylene membrane positioning intramembranous bone-chip implantation, were performed compared control defects. Slight improvement regeneration was demonstrated with subperiosteal ectocranial endocranial membranes, alone or combination, chips combination an outer inner membrane. Virtually complete observed animals receivi...