The Role Of Immunoblasts In Host Resistance And Immunotherapy Of Primary Sarcomata

摘要: Publisher Summary This chapter focuses on the central role of immunoblasts in host resistance and immunotherapy primary sarcomata. The demonstration that nearly all neoplastic cells experimental animals, however induced, contain antigens absent from normal adult their plasma membrane has focused attention mechanisms allow tumor to escape immunological destruction by host. discussion is restricted tumors are demonstrably antigenic which they growing. Even within this field, suppression an established malignant process natural immune reaction only observed animals under special circumstances such as resulting exposure oncogenic virus. effector response confined limits imposed physiological properties different anatomical sites, well amounts cytotoxic antibodies potentially available. Most immunology, presented chapter, based study fibrosarcomata induced rats subcutaneous implantation a pellet 3:4 benzpyrene. Immunoblasts responsible for propagating disseminating throughout body can, thus, generate high titers specific antibody blood serum when transferred unimmunized, syngeneic recipient.