Indications for surgery still exist in asymptomatic primary hyperparathyroidism

摘要: Primary hyperparathyroidism (HPT) has recently proven more common than was anticipated only a few decades ago and an increasing number of patients are now diagnosed with mild hypercalcemia less distinct symptoms. Although liberal indications for parathyroid surgery generally adopted treatment is currently offered to approximately 1/10 HPT in the population. Patients really appear sustain little risk develop classical complications such as hypercalcemic crisis, deteriorated renal function or pronounced loss bone mineral, it been suggested that follow up without may be option apparently asymptomatic HPT. However, majority also even those moderate elevations serum calcium, will upon close examination reveal symptoms neuromuscular weakness, fatigue, depression especially elderly confusion dementia-like disorders. It appreciated disease seems imply increased death cardiovascular disease, which appears reversed by surgery. Thus, should still constitute principal medical surveillance operation chosen selected, mainly hypercalcemia, but then presence symtoms, could favourably affected carefully excluded. Surveillance assure do not disability during long-term up.