Hepatotoxicity and nephrotoxicity evaluation in Wistar albino rats exposed to Morinda lucida leaf extract.

作者: Taofeeq Oduola , Ibrahim Bello , Ganiyu Adeosun , Abdul-Waheed Ademosun , Gassal Raheem

DOI: 10.4297/NAJMS.2010.2230

关键词:

摘要: Background: Aqueous extract of Morinda lucida benth leaf is consumed in Southern Nigeria the treatment malaria without any regard for its safety.

参考文章(15)
Brian D. Andresen, Norbert W. Tietz, Textbook of clinical chemistry W.B. Saunders. ,(1986)
Makinde Jm, Obih Po, Screening of Morinda lucida leaf extract for antimalarial action on Plasmodium berghei berghei in mice. African journal of medicine and medical sciences. ,vol. 14, pp. 59- 63 ,(1985)
L. Tona, N.P. Ngimbi, M. Tsakala, K. Mesia, K. Cimanga, S. Apers, T. De Bruyne, L. Pieters, J. Totté, A.J. Vlietinck, Antimalarial activity of 20 crude extracts from nine African medicinal plants used in Kinshasa, Congo. Journal of Ethnopharmacology. ,vol. 68, pp. 193- 203 ,(1999) , 10.1016/S0378-8741(99)00090-2
Dietrich Lorke, A new approach to practical acute toxicity testing. Archives of Toxicology. ,vol. 54, pp. 275- 287 ,(1983) , 10.1007/BF01234480
G. Zbinden, M. Flury-Roversi, Significance of the LD50-test for the toxicological evaluation of chemical substances Archives of Toxicology. ,vol. 47, pp. 77- 99 ,(1981) , 10.1007/BF00332351
I.U. Asuzu, C.N. Chineme, Effects of Morinda lucida leaf extract on Trypanosoma brucei brucei infection in mice. Journal of Ethnopharmacology. ,vol. 30, pp. 307- 313 ,(1990) , 10.1016/0378-8741(90)90109-7
OLUMAYOKUN A. OLAJIDE, S. OLUBUSAYO AWE, J. MODUPE MAKINDE, OLUGBENGA MOREBISE, Evaluation of the Anti‐diabetic Property of Morinda lucida Leaves in Streptozotocin‐diabetic Rats Journal of Pharmacy and Pharmacology. ,vol. 51, pp. 1321- 1324 ,(2010) , 10.1211/0022357991776903