The Notch Pathway: A Link Between COVID-19 Pathophysiology and Its Cardiovascular Complications
作者： Brenda Lilly , Brenda Lilly , Randa M. Breikaa , Randa M. Breikaa
关键词:
摘要: Coronavirus disease 2019 or COVID-19 has been dominating our lives for a little over year now, affecting every aspect from health, economy to social interactions. In addition known complications of viral infections such as heightened immune responses, presents with serious cardiovascular sequelae that need be urgently addressed. With limited knowledge pathogenesis and how counteract complications, this review highlights critical pathway, the Notch signaling pathway is likely linked COVID-19-associated complications.
frontiersin.org
sci-hub.st 参考文章(162)
Paul S. Masters, The molecular biology of coronaviruses. Advances in Virus Research. ,vol. 66, pp. 193- 292 ,(2006) , 10.1016/S0065-3527(06)66005-3
E S Robertson, J Lin, E Kieff, The amino-terminal domains of Epstein-Barr virus nuclear proteins 3A, 3B, and 3C interact with RBPJ(kappa). Journal of Virology. ,vol. 70, pp. 3068- 3074 ,(1996) , 10.1128/JVI.70.5.3068-3074.1996
Zhengyan Yang, Liang Guo, Dan Liu, Limin Sun, Hongyu Chen, Que Deng, Yanjun Liu, Ming Yu, Yuanfang Ma, Ning Guo, Ming Shi, Acquisition of resistance to trastuzumab in gastric cancer cells is associated with activation of IL-6/STAT3/Jagged-1/Notch positive feedback loop Oncotarget. ,vol. 6, pp. 5072- 5087 ,(2015) , 10.18632/ONCOTARGET.3241
Matteo Cesari, Marco Pahor, Raffaele Antonelli Incalzi, Plasminogen activator inhibitor-1 (PAI-1): a key factor linking fibrinolysis and age-related subclinical and clinical conditions. Cardiovascular Therapeutics. ,vol. 28, ,(2010) , 10.1111/J.1755-5922.2010.00171.X
Jon C Aster, In brief: Notch signalling in health and disease. The Journal of Pathology. ,vol. 232, pp. 1- 3 ,(2014) , 10.1002/PATH.4291
Shiyu Liu, Dawei Liu, Chider Chen, Kazunori Hamamura, Alireza Moshaverinia, Ruili Yang, Yao Liu, Yan Jin, Songtao Shi, MSC Transplantation Improves Osteopenia via Epigenetic Regulation of Notch Signaling in Lupus Cell Metabolism. ,vol. 22, pp. 606- 618 ,(2015) , 10.1016/J.CMET.2015.08.018
Patricia A. Thistlethwaite, Xiaodong Li, Xiaoxue Zhang, Notch Signaling in Pulmonary Hypertension Advances in Experimental Medicine and Biology. ,vol. 661, pp. 279- 298 ,(2010) , 10.1007/978-1-60761-500-2_18
Gary Thomas, Furin at the cutting edge: from protein traffic to embryogenesis and disease. Nature Reviews Molecular Cell Biology. ,vol. 3, pp. 753- 766 ,(2002) , 10.1038/NRM934
Thibaut Quillard, Julie Devallière, Stéphanie Coupel, Béatrice Charreau, Inflammation dysregulates Notch signaling in endothelial cells: Implication of Notch2 and Notch4 to endothelial dysfunction Biochemical Pharmacology. ,vol. 80, pp. 2032- 2041 ,(2010) , 10.1016/J.BCP.2010.07.010
Yong-Chao Ma, Chong Shi, Yao-Nan Zhang, Lan-Ge Wang, Hao Liu, Hong-Ti Jia, Yu-Xiang Zhang, Fazlul H. Sarkar, Ze-Sheng Wang, The Tyrosine Kinase c-Src Directly Mediates Growth Factor-Induced Notch-1 and Furin Interaction and Notch-1 Activation in Pancreatic Cancer Cells PLoS ONE. ,vol. 7, pp. e33414- ,(2012) , 10.1371/JOURNAL.PONE.0033414