Subclinical hypothyroidism and cardiovascular risk: recommendations for treatment.
作者： Irene A. Weiss , Noah Bloomgarden , William H. Frishman
DOI: 10.1097/CRD.0B013E318227DF87
关键词:
摘要: The definition of subclinical hypothyroidism (SCH) is solely biochemical: a serum free T4 level within the reference range in presence an elevated thyroid-stimulating hormone (TSH) level. While overt associated with increased cardiovascular disease risk, SCH, mildest form hypothyroidism, may also be but to lesser degree. Recent evidence points significant trend toward increase risk at higher TSH levels, levels ≥10 mIU/L morbidity and mortality. It generally recommended treat thyroid those individuals SCH values mIU/L. Treatment patients <10 controversial considered selected patients.
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Richard D. Siegel, Stephanie L. Lee, Toxic nodular goiter. Toxic adenoma and toxic multinodular goiter. Endocrinology and Metabolism Clinics of North America. ,vol. 27, pp. 151- 168 ,(1998) , 10.1016/S0889-8529(05)70304-2
N Hamscho, N Döbert, K Zaplatnikov, A Tsolakis, C Menzel, F Grünwald, K Maurer, T Kratzsch, J Diener, J Peters, L Frölich, Subclinical hyperthyroidism in dementia and correlation of the metabolic index in FDG-PET. Acta Medica Austriaca. ,vol. 30, pp. 130- 133 ,(2003)
Nicolas Rodondi, Douglas C. Bauer, Anne R. Cappola, Jacques Cornuz, John Robbins, Linda P. Fried, Paul W. Ladenson, Eric Vittinghoff, John S. Gottdiener, Anne B. Newman, Subclinical Thyroid Dysfunction, Cardiac Function, and the Risk of Heart Failure Journal of the American College of Cardiology. ,vol. 52, pp. 1152- 1159 ,(2008) , 10.1016/J.JACC.2008.07.009
B Dozin, M A Magnuson, V M Nikodem, Thyroid hormone regulation of malic enzyme synthesis. Dual tissue-specific control. Journal of Biological Chemistry. ,vol. 261, pp. 10290- 10292 ,(1986) , 10.1016/S0021-9258(18)67522-2
Belinda J. Schouten, Bevan E. W. Brownlie, Chris M. Frampton, John G. Turner, Subclinical thyrotoxicosis in an outpatient population – predictors of outcome Clinical Endocrinology. ,vol. 74, pp. 257- 261 ,(2011) , 10.1111/J.1365-2265.2010.03908.X
Grzegorz Kaminski, Dariusz Michalkiewicz, Karol Makowski, Zbigniew Podgajny, Norbert Szalus, Marek Ruchala, Ewelina Szczepanek, Grzegorz Gielerak, Prospective echocardiographic evaluation of patients with endogenous subclinical hyperthyroidism and after restoring euthyroidism Clinical Endocrinology. ,vol. 74, pp. 501- 507 ,(2011) , 10.1111/J.1365-2265.2010.03957.X
M. Ciaccheri, F. Cecchi, C. Arcangeli, A. Dolara, A. Zuppiroli, C. Pieroni, Occult thyrotoxicosis in patients with chronic and paroxysmal isolated atrial fibrillation Clinical Cardiology. ,vol. 7, pp. 413- 416 ,(1984) , 10.1002/CLC.4960070706
Anne R. Cappola, Linda P. Fried, Alice M. Arnold, Mark D. Danese, Lewis H. Kuller, Gregory L. Burke, Russell P. Tracy, Paul W. Ladenson, Thyroid Status, Cardiovascular Risk, and Mortality in Older Adults JAMA. ,vol. 295, pp. 1033- 1041 ,(2006) , 10.1001/JAMA.295.9.1033
MD Gammage, JV Parle, RL Holder, LM Roberts, FDR Hobbs, Sue Wilson, MC Sheppard, JA Franklyn, Association between serum free thyroxine concentration and atrial fibrillation. JAMA Internal Medicine. ,vol. 167, pp. 928- 934 ,(2007) , 10.1001/ARCHINTE.167.9.928
Toshihiro Ichiki, Thyroid hormone and atherosclerosis. Vascular Pharmacology. ,vol. 52, pp. 151- 156 ,(2010) , 10.1016/J.VPH.2009.09.004