Laser Doppler measurement of cutaneous blood flow.

作者: G Allen. Holloway , Dennis W. Watkins

DOI: 10.1111/1523-1747.EP12507665

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摘要: This work describes an instrument for the noninvasive measurement of cutaneous blood flow velocity. The system utilizes Doppler shift laser light backscattered from moving red cells in microcirculation, being obtained by optical heterodyning technique. Comparison is made between this technique and 133 xenon clearance measuring forearms normal volunteers. Variations were inducing different degrees solar erythema with ultraviolet sunlamp. A Y on X linear regression yielded a coefficient=0.89 (p n = 16) two methods. method appears to represent practical clinical evaluation any skin surface.

参考文章(9)
George B. Benedek, Benjamin Ross, Charles Riva, Laser Doppler measurements of blood flow in capillary tubes and retinal arteries. Investigative Ophthalmology & Visual Science. ,vol. 11, pp. 936- 944 ,(1972)
Y. Yeh, H. Z. Cummins, LOCALIZED FLUID FLOW MEASUREMENTS WITH AN He–Ne LASER SPECTROMETER Applied Physics Letters. ,vol. 4, pp. 176- 178 ,(1964) , 10.1063/1.1753925
T. Tanaka, C. Riva, I. Ben-Sira, Blood Velocity Measurements in Human Retinal Vessels Science. ,vol. 186, pp. 830- 831 ,(1974) , 10.1126/SCIENCE.186.4166.830
John E. Chimoskey, G. Allen Holloway, William J. Flanagan, Effect Of Fluocinolone Acetonide Cream On Human Skin Blood Flow Journal of Investigative Dermatology. ,vol. 65, pp. 241- 243 ,(1975) , 10.1111/1523-1747.EP12598260
John E. Chimoskey, William Flanagan, Ultraviolet-Induced Cutaneous Hyperemia and Steroid-Induced Cutaneous Hypoemia Measured by Xenon 133 Disappearance in Dogs Journal of Investigative Dermatology. ,vol. 63, pp. 362- 368 ,(1974) , 10.1111/1523-1747.EP12680855
G. A. Holloway, C. H. Daly, D. Kennedy, J. Chimoskey, Effects of external pressure loading on human skin blood flow measured by 133Xe clearance Journal of Applied Physiology. ,vol. 40, pp. 597- 600 ,(1976) , 10.1152/JAPPL.1976.40.4.597
J. E. Chimoskey, Skin blood flow by 133 Xe disappearance validated by venous occlusion plethysmography Journal of Applied Physiology. ,vol. 32, pp. 432- 435 ,(1972) , 10.1152/JAPPL.1972.32.3.432