Intracellular localization of estrogens in chick liver: increase of the binding sites for the hormone on repeated treatment of the birds with the hormone.
作者： K.K. Sen , P.D. Gupta , G.P. Talwar
DOI: 10.1016/0022-4731(75)90110-7
关键词:
摘要: Binding of [2,4,6,7-3H]-estradiol or its metabolites in the liver tissue unprimed roosters and those given repeated doses estradiol has been studied. Electron autoradiographs show localization radioactivity on endoplasmic reticulum, mitochondria, nuclear membrane nucleolar extranucleolar chromatin hepatocytes. Repeated hormone to bird increase number binding sites. However, dissociation constant (Kd) for heavy pellet fraction extractable with 0·4 M KC1 remains essentially unchanged.
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sci-hub.se 参考文章(21)
C. W. BUNN, Life from Crystals Nature. ,vol. 236, pp. 239- 240 ,(1972) , 10.1038/236239A0
G. P. Talwar, A. D. Krishnan, P. D. Gupta, Quantitative Evaluation of the Progress of Intracellular Infection In Vitro: Incorporation of 3H-Thymidine into Deoxyribonucleic Acid by Mycobacterium leprae in Cultivated Blood Monocytes Infection and Immunity. ,vol. 9, pp. 187- 191 ,(1974) , 10.1128/IAI.9.1.187-191.1974
George Scatchard, The Attractions of Proteins for Small Molecules and Ions Annals of the New York Academy of Sciences. ,vol. 51, pp. 660- 672 ,(1949) , 10.1111/J.1749-6632.1949.TB27297.X
WALTER E. STUMPF, Nuclear Concentration of 3H-estradiol in Target Tissues. Dry-Mount Autoradiography of Vagina, Oviduct, Ovary, Testis, Mammary Tumor, Liver and Adrenal Endocrinology. ,vol. 85, pp. 31- 37 ,(1969) , 10.1210/ENDO-85-1-31
G. Beuving, M. Gruber, Induction of phosvitin synthesis in roosters by estradiol injection Biochimica et Biophysica Acta. ,vol. 232, pp. 529- 536 ,(1971) , 10.1016/0005-2787(71)90607-1
J. H. Clark, J. Gorski, Ontogeny of the estrogen receptor during early uterine development. Science. ,vol. 169, pp. 76- 78 ,(1970) , 10.1126/SCIENCE.169.3940.76
Akhouri A. Sinha, Clyde E. Blackard, Richard P. Doe, Ulysses S. Seal, The in vitro localization of H3 estradiol in human prostatic carcinoma.An electron microscopic autoradiographic study Cancer. ,vol. 31, pp. 682- 688 ,(1973) , 10.1002/1097-0142(197303)31:3<682::AID-CNCR2820310330>3.0.CO;2-2
Jan Mester, Etienne-Emile Baulieu, Nuclear estrogen receptor of chick liver. Biochimica et Biophysica Acta. ,vol. 261, pp. 236- 244 ,(1972) , 10.1016/0304-4165(72)90334-0
JOST BRÖKELMANN, PEROXIDASE-ASSOCIATED BINDING OF ESTRADIOL BY THE RAT UTERUS Journal of Histochemistry and Cytochemistry. ,vol. 17, pp. 394- 407 ,(1969) , 10.1177/17.6.394
R. J. B. KING, J. GORDON, THE ASSOCIATION OF [6,7-3H]OESTRADIOL WITH A NUCLEAR PROTEIN Journal of Endocrinology. ,vol. 39, pp. 533- 542 ,(1967) , 10.1677/JOE.0.0390533