Growing Old and Immunity to Bacteria

摘要: This chapter discusses immune function and its association with increased susceptibility of the elderly to bacterial infections. It is divided based upon common sites infection, an emphasis on pulmonary gastrointestinal Within each section, prevalence infection in population discussed, followed by our current understanding immunity elderly. The pathogens S. pneumoniae, M. tuberculosis, L. monocytogenes are primary focus this chapter. Foodborne important public health concern include such as Campylobacter, Listeria, Shigella, Salmonella. In some individuals, ocular can lead keratitis, a more debilitating disease. at risk developing septicemia following listed 10th leading cause death Although systemic LPS delivery has been model further it cannot responses whole bacteria where interplay between pathogen adds complexity than one single pathogen-associated virulence factor. potential for be used biological weapons already realized, particularly susceptible. Our ability protect from highly dependent generation knowledge about how respond infectious disease additional research warranted.