Ovarian Proteolytic Enzymes and Ovulation

摘要: Mammalian ovulation is a dynamic phenomenon which requires disruption of the vascular system and displacement connective tissue in wall Graafian follicle as ovum released. In most mammals, whole protrudes more markedly from ovarian surface at time ovulation, many instances thin translucent stigma, macula pellucida, forms apex final sign impending rupture. This unusual morphological change has left striking impression on those who have actually observed it. Kelly (1931) was so fascinated while observing rabbit near rupture he stated “as tension within increases, transparent portion around pole begins to bulge. . It now stands out like nipple breast.” The moment sometimes appears an explosive event, leading observers compare it “volcano erupting” (Hill et al., 1935) or “blister that bursts” (Blandau, 1966). There are several reports provide detailed accounts macroscopic microscopic changes occur during this process (Walton Hammond, 1928; Blandau, Until past decade little progress been made elucidation actual mechanism follicular Lack knowledge On important event reproductive probably due fact experimental approach studies conducted prior 1960 limited visual histological observations follicle. But even based comprehensive yielded indecisive opinions “the results these experiments were either negative inconsistent [the investigators] unable produce any conclusive evidence” (Guttmacher Guttmacher, 1921), problem still remains condition uncertainty” (Kraus, 1947). As Hisaw (1961) counseled dozen years ago, solution may be found by investigating basic physiological processes go follicle.” information presented symposium, Dr. Nalbandov timely organized, reveals steps taken right direction.