Evaluation of fenitrothion for the control of malaria.

摘要: Fenitrothion was evaluated for residual spraying in antimalaria programmes a large-scale field trial near Kisumu, Kenya from 1972 to 1976. The insecticide applied hyper/holoendemic malarious area of 200 km(2) inhabited by about 50 000 people. All houses and animal shelters were sprayed at target dosage rate 2 g/m(2) 3-month intervals total 8 consecutive spray rounds years. malaria vectors Anopheles gambiae species A B A. funestus reduced negligible densities indoors outdoors immediately after initiation 10 months the last round. However, reappeared during main wet season high enough reestablish low-level transmission short periods. Spraying produced marked rapid decrease both incidence prevalence malaria. daily probability acquiring infection 0.009 before 0.0003 under protection, reduction 96%. Data collected on longitudinal basis indicated that sustained protection would reduce an asymptotic limit 6.9% assumption inoculation recovery rates remain stable. attain eradication this type epidemiological situation, complementary measures such as mass drug administration appear be necessary.