摘要: The mitotic spindle is a microtubule-made machine required for chromosome segregation during mitosis. Several pathways and molecules contribute to the assembly of this structure, which shows intrinsic dynamic properties. nature microtubules plays key role in error correction, as well generation force necessary move chromosomes. Additionally, several molecular motors use tracks and, together with microtubule stabilizing destabilizing proteins, they participate proper function. Here we summarize essential concepts principles behind formation robust machine.
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