Myocardial fibrosis and diastolic dysfunction in deoxycorticosterone acetate-salt hypertensive rats is ameliorated by the peroxisome proliferator-activated receptor-alpha activator fenofibrate, partly by suppressing inflammatory responses associated with the nuclear factor-kappa-b pathway

作者: Takehiro Ogata , Takashi Miyauchi , Satoshi Sakai , Masakatsu Takanashi , Yoko Irukayama-Tomobe

DOI: 10.1016/J.JACC.2003.11.043

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摘要: AbstractObjectives: We sought to clarify that a peroxisome proliferator-activated receptor-alpha (PPAR-alpha) activator inhibits myocardial fibrosis and its resultant diastolic dysfunction in hyper...

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