Unzipping the dimer in primary amides by cocrystallization with sulfoxides
作者： Kevin S. Eccles , Curtis J. Elcoate , Anita R. Maguire , Simon E. Lawrence
DOI: 10.1021/CG2006277
关键词:
摘要: A systematic crystal engineering study was undertaken to investigate how different electronic substituents on the aromatic ring of primary amides impact ability amide cocrystallize with dibenzyl sulfoxide. Amides which sulfoxide form 1:1 cocrystals containing a discrete N–H···O═S supramolecular synthon as well well-known C(4) chain. The combination these two synthons gives rise linear chains molecules, each molecule capped by one molecule. Thus, R22(8) dimer typically seen for is no longer present in cocrystals. influence effects similar that observed acids
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