Human IgG in immune complexes bound to human erythrocyte CR1 is recognized differently than human IgG bound to an erthrocyte surface antigen

作者: Craig J. Reist , Jacqueline D. Wright , Ronald H. Labuguen , Ronald P. Taylor

DOI: 10.1016/0022-1759(93)90123-O

关键词:

摘要: We have developed several methods, including a new use of magnetic cell separation techniques, to examine how human IgG bound erythrocytes can be recognized. find that in complement-opsonized immune complexes erythrocyte CR1 is less accessible probes than the rhesus antigen on erythrocytes. These findings suggest mechanism by which are removed and cleared from circulation different mechanisms lead splenic clearance sensitized

参考文章(30)
J Chevalier, M D Kazatchkine, Distribution in clusters of complement receptor type one (CR1) on human erythrocytes. Journal of Immunology. ,vol. 142, pp. 2031- 2036 ,(1989)
J A Schifferli, J P Paccaud, J L Carpentier, Direct evidence for the clustered nature of complement receptors type 1 on the erythrocyte membrane. Journal of Immunology. ,vol. 141, pp. 3889- 3894 ,(1988)
F Pocanic, E L Wright, R P Taylor, Quantitative analyses of C3b capture and immune adherence of IgM antibody/dsDNA immune complexes. Journal of Immunology. ,vol. 143, pp. 3626- 3631 ,(1989)
J J O'Shea, M M Frank, B E Seligmann, E J Brown, J I Gallin, J A Metcalf, Evidence for distinct intracellular pools of receptors for C3b and C3bi in human neutrophils Journal of Immunology. ,vol. 134, pp. 2580- 2587 ,(1985)
J C Edberg, E Wright, R P Taylor, Quantitative analyses of the binding of soluble complement-fixing antibody/dsDNA immune complexes to CR1 on human red blood cells. Journal of Immunology. ,vol. 139, pp. 3739- 3747 ,(1987)
Joseph M. Ahearn, Douglas T. Fearon, Structure and function of the complement receptors, CR1 (CD35) and CR2 (CD21). Advances in Immunology. ,vol. 46, pp. 183- 219 ,(1989) , 10.1016/S0065-2776(08)60654-9
G. Spangrude, S Heimfeld, I. Weissman, Purification and Characterization of Mouse Hematopoietic Stem Cells Science. ,vol. 241, pp. 58- 62 ,(1988) , 10.1126/SCIENCE.2898810
Ronald P. Taylor, Franciska Pocanic, Craig Reist, Eleanor L. Wright, Complement-opsonized IgG antibody/dsDNA immune complexes bind to CR1 clusters on isolated human erythrocytes Clinical Immunology and Immunopathology. ,vol. 61, pp. 143- 160 ,(1991) , 10.1016/S0090-1229(05)80020-0
Fernando G. Cosio, Shen Xiao-Ping, Lee A. Hebert, Immune complexes bind preferentially to specific subpopulations of human erythrocytes Clinical Immunology and Immunopathology. ,vol. 55, pp. 337- 354 ,(1990) , 10.1016/0090-1229(90)90123-8