Therapeutic implications of novel peptides targeting ER-mitochondria Ca2+-flux systems.
作者： Martijn Kerkhofs , Geert Bultynck , Tim Vervliet , Giovanni Monaco
DOI: 10.1016/J.DRUDIS.2019.03.020
关键词:
摘要: … This can cause cell death but in some cases it is a trigger for … -2 without directly activating Bax/Bak. Venetoclax was recently … mPTP-dependent intracellular Ca 2+ spike and necrotic cell …
sci-hub.se 
kuleuven.be 参考文章(169)
Jan B. Parys, Humbert De Smedt, Inositol 1,4,5-Trisphosphate and Its Receptors Advances in Experimental Medicine and Biology. ,vol. 740, pp. 255- 279 ,(2012) , 10.1007/978-94-007-2888-2_11
Horng H. Chen, James F. Glockner, John A. Schirger, Alessandro Cataliotti, Margaret M. Redfield, John C. Burnett, Novel protein therapeutics for systolic heart failure: chronic subcutaneous B-type natriuretic peptide. Journal of the American College of Cardiology. ,vol. 60, pp. 2305- 2312 ,(2012) , 10.1016/J.JACC.2012.07.056
Sadaf Farsinejad, Zohre Gheisary, Sanaz Ebrahimi Samani, Ali Mohammad Alizadeh, Mitochondrial targeted peptides for cancer therapy. Tumor Biology. ,vol. 36, pp. 5715- 5725 ,(2015) , 10.1007/S13277-015-3719-1
Michael J. Berridge, Peter Lipp, Martin D. Bootman, The versatility and universality of calcium signalling Nature Reviews Molecular Cell Biology. ,vol. 1, pp. 11- 21 ,(2000) , 10.1038/35036035
Jean‐Michel Pawlotsky, Robert Flisiak, Shiv K Sarin, Jens Rasenack, Teerha Piratvisuth, Wan‐Long Chuang, Cheng‐Yuan Peng, Graham R Foster, Samir Shah, Heiner Wedemeyer, Christophe Hézode, Wei Zhang, Kelly A Wong, Bin Li, Claudio Avila, Nikolai V Naoumov, VITAL‐1 study team, None, Alisporivir plus ribavirin, interferon free or in combination with pegylated interferon, for hepatitis C virus genotype 2 or 3 infection. Hepatology. ,vol. 62, pp. 1013- 1023 ,(2015) , 10.1002/HEP.27960
Ji-Young Kim, Ji Hye Han, Ae-Ran Moon, Jung Hee Park, Jeong Hwan Chang, Jeehyeon Bae, Tae-Hyoung Kim, Minimal killing unit of the mitochondrial targeting domain of Noxa Journal of Peptide Science. ,vol. 19, pp. 485- 490 ,(2013) , 10.1002/PSC.2525
Tim Vervliet, Jan B. Parys, Geert Bultynck, Bcl-2 and FKBP12 bind to IP3 and ryanodine receptors at overlapping sites: the complexity of protein-protein interactions for channel regulation. Biochemical Society Transactions. ,vol. 43, pp. 396- 404 ,(2015) , 10.1042/BST20140298
R Rizzuto, M Brini, M Murgia, T Pozzan, Microdomains with high Ca2+ close to IP3-sensitive channels that are sensed by neighboring mitochondria Science. ,vol. 262, pp. 744- 747 ,(1993) , 10.1126/SCIENCE.8235595
John W. Elrod, Renee Wong, Shikha Mishra, Ronald J. Vagnozzi, Bhuvana Sakthievel, Sanjeewa A. Goonasekera, Jason Karch, Scott Gabel, John Farber, Thomas Force, Joan Heller Brown, Elizabeth Murphy, Jeffery D. Molkentin, Cyclophilin D controls mitochondrial pore–dependent Ca2+ exchange, metabolic flexibility, and propensity for heart failure in mice Journal of Clinical Investigation. ,vol. 120, pp. 3680- 3687 ,(2010) , 10.1172/JCI43171
David Karnak, Liang Xu, Chemosensitization of Prostate Cancer by Modulating Bcl-2 Family Proteins Current Drug Targets. ,vol. 11, pp. 699- 707 ,(2010) , 10.2174/138945010791170888