Teratology : Principles and Techniques

作者: James G. Wilson

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摘要: against in¬ vasion of virus, intracellular repro¬ duction, and propagation persistance virus in the host. His data on role temperature tissue inactivation nonspecific hibitors have drawn much attention. Serious objections been raised to his infections RNA influenza virus. It must be stressed here that similar data, published five years ago by Portocala et al (Acta Virologica 3:172, 1959) Maasa (Proc Nat Acad Sci USA 5:877, 1959), not confirmed subsequent publications. The general discussion completed symposium (pp 344-354) touched a number questions, particularly code ca¬ pacity (volume) genome. According note Fazekas de St. Groth 344-345), protein isolated Laver early Scholtissek Rott account for 6,000 nucleotides form fluenza RNA. I consider this calcu¬ lation disputable because it does possible periodic structure some proteins (hemagglutinin, neuraminidase) may consist smaller monomers. An attempt possibility has made reviewer (Zhdanov: Lancet 2:738, 1965), though is also disputable. In particular, newer hemagglutinin (Graf Zhdanov, published) suggests molecular weight estimates low therefore cystron(s) responsible would lesser volume viral

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