Stenting versus Endarterectomy for Treatment of Carotid-Artery Stenosis

摘要: For 2502 patients over a median follow-up period of 2.5 years, there was no significant difference in the estimated 4-year rates primary end point between stenting group and endarterectomy (7.2% 6.8%, respectively; hazard ratio with stenting, 1.11; 95% confidence interval, 0.81 to 1.51; P = 0.51). There differential treatment effect regard according symptomatic status (P 0.84) or sex 0.34). The rate stroke death 6.4% 4.7% (hazard ratio, 1.50; 0.03); among were 8.0% 1.37; 0.14), asymptomatic 4.5% 2.7% 1.86; 0.07), respectively. Periprocedural individual components points differed group: for (0.7% vs. 0.3%, 0.18), (4.1% 2.3%, 0.01), myocardial infarction (1.1% 0.03). After this period, incidences ipsilateral similarly low (2.0% 2.4%, 0.85). CONCLUSIONS Among carotid stenosis, risk composite outcome stroke, infarction, did not differ significantly undergoing carotid-artery endarterectomy. During periprocedural higher (ClinicalTrials.gov number, NCT00004732.)