Homologous calcium-binding proteins in the activation of skeletal, cardiac, and smooth muscle myosin light chain kinases.

作者: M.P. Walsh , B. Vallet , J.C. Cavadore , J.G. Demaille

DOI: 10.1016/S0021-9258(19)86172-0

关键词:

摘要: In order to identify the physiological regulator of calcium dependent myosin light chain kinases cardiac, skeletal, and smooth muscles, effects three homologous calciproteins, calmodulin, troponin C, parvalbumin, on isolated from bovine myocardium, rabbit skeletal muscle, turkey gizzard were examined. Only calmodulin was effective in stimulating or muscle kinase; C parvalbumin exhibited no activation any kinases, even when examined at concentrations as high 10-(5) M. It is concluded that specific kinase muscle.

参考文章(30)
W. T. Perrie, S. V. Perry, An electrophoretic study of the low-molecular-weight components of myosin Biochemical Journal. ,vol. 119, pp. 31- 38 ,(1970) , 10.1042/BJ1190031
R J Grand, S V Perry, R A Weeks, Troponin C-like proteins (calmodulins) from mammalian smooth muscle and other tissues Biochemical Journal. ,vol. 177, pp. 521- 529 ,(1979) , 10.1042/BJ1770521
Jackie D. Corbin, Erwin M. Reimann, [41] Assay of cyclic AMP-dependent protein kinases Methods in Enzymology. ,vol. 38, pp. 287- 290 ,(1974) , 10.1016/0076-6879(74)38044-5
Marion L. Greaser, John Gergely, Purification and Properties of the Components from Troponin Journal of Biological Chemistry. ,vol. 248, pp. 2125- 2133 ,(1973) , 10.1016/S0021-9258(19)44195-1
J R Dedman, J D Potter, A R Means, Biological cross-reactivity of rat testis phosphodiesterase activator protein and rabbit skeletal muscle troponin-C. Journal of Biological Chemistry. ,vol. 252, pp. 2437- 2440 ,(1977) , 10.1016/S0021-9258(17)40572-2
M.P. Walsh, B. Vallet, F. Autric, J.G. Demaille, Purification and characterization of bovine cardiac calmodulin-dependent myosin light chain kinase. Journal of Biological Chemistry. ,vol. 254, pp. 12136- 12144 ,(1979) , 10.1016/S0021-9258(19)86440-2
Tian Seng Teo, Teresa H. Wang, Jerry H. Wang, Purification and Properties of the Protein Activator of Bovine Heart Cyclic Adenosine 3′,5′-Monophosphate Phosphodiesterase Journal of Biological Chemistry. ,vol. 248, pp. 588- 595 ,(1973) , 10.1016/S0021-9258(19)44414-1