Evaluation of pulmonary ventilation in COVID-19 patients using oxygen-enhanced three-dimensional ultrashort echo time MRI: a preliminary study.

摘要: AIM To evaluate the lung function of coronavirus disease 2019 (COVID-19) patients using oxygen-enhanced (OE) ultrashort echo time (UTE) MRI. MATERIALS AND METHODS Forty-nine with COVID-19 were included in study. The OE-MRI was based on a respiratory-gated three-dimensional (3D) radial UTE sequence. For each patient, percent signal enhancement (PSE) map calculated expression PSE = (S100% – S21%)/S21%, where S21% and S100% are signals acquired during room air 100% oxygen inhalation, respectively. Agreement lesion detectability between UTE-MRI computed tomography (CT) performed kappa test. Mann–Whitney U-test used to difference mean mild-type common-type COVID-19. Spearman's test assess relationship size. Furthermore, region interest (ROI) normal pulmonary parenchyma lesions. Kruskal–Wallis applied different types. RESULTS CT reached good agreement detectability. Ventilation measures (5.3 ± 5.5%) significantly from those (3 ± 3.9%). Besides, there no significant correlation lesions (3.2 ± 4.9%) lower than that (5.4 ± 3.9%). No found among CONCLUSION OE-UTE-MRI could serve as promising method for assessment or treatment management patients.