Viral Subversion of the Immune System

摘要: The continuous interactions between host and viruses during their co-evolution have shaped not only the immune system but also countermeasures used by viruses. Studies in last decade described diverse arrays of pathways molecular targets that are to elude detection or destruction, both. These include targeting for major histocompatibility complex class I II antigen presentation, natural killer cell recognition, apoptosis, cytokine signalling, complement activation. This paper provides an overview viral immune-evasion mechanisms date. It highlights contribution this field our understanding system, importance aspect biology infection develop efficacious safe vaccines.