Myocardial protection afforded by nicorandil and ischaemic preconditioning in a rabbit infarct model in vivo.
作者： Jun-ichi Imagawa , Gary F. Baxter , Derek M. Yellon
DOI: 10.1097/00005344-199801000-00011
关键词:
摘要: Summary:We previously showed that preoperative nicorandil, a hybrid potassium channel opener and nitrate compound, conferred cardioprotective effects in hypoxia/reoxygenation model of isolated human atrial muscle by using functional recovery as an end point, ischaemic preconditioning surp
lww.com 
sci-hub.st 参考文章(25)
M Hiraoka, Z Fan, Activation of ATP-sensitive outward K+ current by nicorandil (2-nicotinamidoethyl nitrate) in isolated ventricular myocytes. Journal of Pharmacology and Experimental Therapeutics. ,vol. 250, pp. 278- 285 ,(1989)
T Mizumura, Infarct size-reducing effect of nicorandil is mediated by the KATP channel but not by its nitrate-like properties in dogs. Cardiovascular Research. ,vol. 32, pp. 274- 285 ,(1996) , 10.1016/0008-6363(96)00061-2
D.M. Yellon, G.F. Baxter, M.S. Marber, Angina reassessed: pain or protector? The Lancet. ,vol. 347, pp. 1159- 1162 ,(1996) , 10.1016/S0140-6736(96)90613-3
Eiji HAMADA, Reiko TAKIKAWA, Hiroyuki ITO, Mari IGUCHI, Akira TERANO, Tsuneaki SUGIMOTO, Yoshihisa KURACHI, GLIBENCLAMIDE SPECIFICALLY BLOCKS ATP-SENSITIVE K+ CHANNEL CURRENT IN ATRIAL MYOCYTES OF GUINEA PIG HEART Japanese Journal of Pharmacology. ,vol. 54, pp. 473- 477 ,(1990) , 10.1254/JJP.54.473
Toshihiko IIJIMA, Masao ENDOH, Norio TAIRA, Differential effects of isoproterenol on the canine atrial action potential in the presence of carbachol or nicorandil. Japanese Journal of Pharmacology. ,vol. 44, pp. 218- 221 ,(1987) , 10.1254/JJP.44.218
C. S. Carr, D. M. Yellon, Ischaemic preconditioning may abolish the protection afforded by ATP-sensitive potassium channel openers in isolated human atrial muscle Basic Research in Cardiology. ,vol. 92, pp. 252- 260 ,(1997) , 10.1007/BF00788520
C. F Toombs, T. L Moore, R. J Shebuski, Limitation of infarct size in the rabbit by ischaemic preconditioning is reversible with glibenclamide Cardiovascular Research. ,vol. 27, pp. 617- 622 ,(1993) , 10.1093/CVR/27.4.617
Kenji Hashimoto, Masahiko Kinoshita, Yasunori Ohbayashi, Coronary effects of nicorandil in comparison with nitroglycerin in chronic conscious dogs. Cardiovascular Drugs and Therapy. ,vol. 5, pp. 131- 138 ,(1991) , 10.1007/BF03029808
Teruyuki YANAGISAWA, Keisuke SATOH, Norio TAIRA, Circumstantial evidence for increased potassium conductance of membrane of cardiac muscle by 2-nicotinamidoethyl nitrate (SG-75). Japanese Journal of Pharmacology. ,vol. 29, pp. 687- 694 ,(1979) , 10.1254/JJP.29.687
Masahiko Kinoshita, Shunsuke Nishikawa, Matsuhiko Sawamura, Shinichiro Yamaguchi, Kenichi Mitsunami, Makoto Itoh, Masakazu Motomura, Keizo Bito, Iwao Mashiro, Seiichi Kawakita, Comparative efficacy of high-dose versus low-dose nicorandil therapy for chronic stable angina pectoris. American Journal of Cardiology. ,vol. 58, pp. 733- 738 ,(1986) , 10.1016/0002-9149(86)90347-4