Nuclear structures of primary malignant lymphoma in the brain

作者: Eiichi Tani , Toshio Ametani , Yasuo Kawamura , Hajime Handa

DOI: 10.1002/1097-0142(196909)24:3<617::AID-CNCR2820240329>3.0.CO;2-H

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摘要: Various classes of nuclear granules and inclusion bodies were observed in primary malignant lymphoma cells the brain. In addition to chromatin nucleoli, perichromatin unusual dense main granular structures. However, most prominent features clusters interchromatin granules. The individual round or ovoid, sometimes filamentous shape, about 30 40 mμ diameter. They not extractable enzyme digestion with pepsin, RNAase, DNAase, decreased markedly electron density when both pepsin RNAase employed. It may be reasonably assumed that a complex RNA acidic proteins. Some involved formation. This study suggest 2 possible processes formation bodies, which are derived (a) from substances (b) inner membranes.

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