Safety and efficacy of liver resections in elderly patients.

作者: Stylianos Kykalos , Georgios C Sotiropoulos , Gregory Kouraklis , Ioannis D Kostakis , Nikolaos Machairas

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摘要: PURPOSE Elderly patients constitute a special group of surgical candidates due to the frequent coexistence major comorbidities. We report our experience in performing liver resections aged 75 years or older. METHODS During period 62 months, 154 underwent resections, out which 20 were old Our prospectively maintained database was reviewed regarding patient and tumor characteristics, intraoperative postoperative data. RESULTS Out older, 15 men 5 women, with mean age 79.3 years. Sixteen (80%) had at least one comorbidity. Indications for surgery hepatocellular carcinoma (n=5), intrahepatic cholangiocarcinoma (n=7), metastases abscess (n=2) cyst hemorrhage (n=1). Liver included 3 left hepatectomies, 1 lateral hepatectomy combined segmentectomy wedge resection, 2 right central hepatectomy, 4 bisegmentectomies, segmentectomies, unroofings giant cysts. In 10 operations, further procedures apart from resection. Six postoperatively admitted intensive care unit days. Postoperative bile leak documented patient, no reoperation needed. No death recorded during hospitalization patients. The length hospital stay 12.9 CONCLUSIONS even ones, can be tolerated by elderly good outcomes under presupposition careful selection.

参考文章(35)
Robert M. Cannon, Robert C. G. Martin, Glenda G. Callender, Kelly M. McMasters, Charles R. Scoggins, Safety and efficacy of hepatectomy for colorectal metastases in the elderly. Journal of Surgical Oncology. ,vol. 104, pp. 804- 808 ,(2011) , 10.1002/JSO.22042
Kevin Phan, Vincent Vinh Gia An, Hakeem Ha, Steven Phan, Vincent Lam, Henry Pleass, Hepatic resection for malignant liver tumours in the elderly: a systematic review and meta-analysis. Anz Journal of Surgery. ,vol. 85, pp. 815- 822 ,(2015) , 10.1111/ANS.13211
Kazuhiro Kondo, Kazuo Chijiiwa, Mayumi Funagayama, Masahiro Kai, Kazuhiro Otani, Jiro Ohuchida, Hepatic Resection is Justified for Elderly Patients with Hepatocellular Carcinoma World Journal of Surgery. ,vol. 32, pp. 2223- 2229 ,(2008) , 10.1007/S00268-008-9688-4
Antoine Guillaud, Bernard Meunier, Karim Boudjema, Laurent Sulpice, Michel Rayar, Boris Campillo, Claire Pery, Advanced Age Remains an Achilles Heel for Liver Resections World Journal of Surgery. ,vol. 38, pp. 918- 926 ,(2014) , 10.1007/S00268-013-2367-0
Srinevas K. Reddy, Andrew S. Barbas, Ryan S. Turley, T. Clark Gamblin, David A. Geller, J. Wallis Marsh, Allan Tsung, Bryan M. Clary, Sandhya Lagoo-Deenadayalan, Major Liver Resection in Elderly Patients: A Multi-Institutional Analysis Journal of the American College of Surgeons. ,vol. 212, pp. 787- 795 ,(2011) , 10.1016/J.JAMCOLLSURG.2010.12.048
Hiroaki Motoyama, Akira Kobayashi, Takahide Yokoyama, Akira Shimizu, Hiroshi Sakai, Norihiko Furusawa, Tsuyoshi Notake, Noriyuki Kitagawa, Takuma Arai, Kenta Yokoi, Yohei Okubo, Shin-ichi Miyagawa, Impact of advanced age on the short- and long-term outcomes in patients undergoing hepatectomy for hepatocellular carcinoma: a single-center analysis over a 20-year period. American Journal of Surgery. ,vol. 209, pp. 733- 741 ,(2015) , 10.1016/J.AMJSURG.2014.05.026
Hai-Qing Wang, Jian Yang, Lu-Nan Yan, Xiao-Wu Zhang, Jia-Yin Yang, Liver resection in hepatitis B related-hepatocellular carcinoma: clinical outcomes and safety in elderly patients. World Journal of Gastroenterology. ,vol. 20, pp. 6620- 6625 ,(2014) , 10.3748/WJG.V20.I21.6620
Mary E. Charlson, Peter Pompei, Kathy L. Ales, C.Ronald MacKenzie, A new method of classifying prognostic comorbidity in longitudinal studies: Development and validation☆ Journal of Chronic Diseases. ,vol. 40, pp. 373- 383 ,(1987) , 10.1016/0021-9681(87)90171-8
Andrea Fontani, Jacopo Martellucci, Serenella Civitelli, Gabriello Tanzini, Outcome of surgical treatment of colorectal cancer in the elderly Updates in Surgery. ,vol. 63, pp. 233- 237 ,(2011) , 10.1007/S13304-011-0085-4
Jong Man Kim, Bong Ick Cho, Choon Hyuck David Kwon, Jae-Won Joh, Jae Berm Park, Joon Hyeok Lee, Sung Joo Kim, Seung Woon Paik, Cheol Keun Park, Hepatectomy is a reasonable option for older patients with hepatocellular carcinoma American Journal of Surgery. ,vol. 209, pp. 391- 397 ,(2015) , 10.1016/J.AMJSURG.2013.06.010