Conversion of Calcineurin Inhibitors With Mammalian Target of Rapamycin Inhibitors After Kidney Transplant

摘要: One way to overcome chronic allograft nephropathy induced by calcineurin inhibitors in immunosuppression protocols for organ transplants is replace such with mammalian target of rapamycin inhibitors, which are not clinically nephrotoxic because they have better renal function. If patients tolerate replacement, there could be a clear preference as maintenance immunosuppressant after transplant. This replacement sufficient if it were used certain time inhibitors. review considers the conversion effects from view point kidney function during different periods