作者: Gregory F. Guzauskas , Denise M. Boudreau , Kathleen F. Villa , Steven R. Levine , David L. Veenstra
DOI: 10.1161/STROKEAHA.111.648238
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摘要: Background and Purpose—Primary stroke centers (PSC) have demonstrated improved survival in patients with acute ischemic (AIS). The objective of this study was to evaluate the cost-effectiveness treating AIS a PSC compared nonPSC hospital setting. Methods—We developed decision analytic model project lifetime outcomes costs 2 hypothetical cohorts 75 patients. Clinical data were derived from recent observational comparing PSC- nonPSC-admitted patients, clinical trials, longitudinal cohort studies, health state preference studies. Cost based on Medicare reimbursement other published sources. We used healthcare payer perspective, primary incremental life expectancy, quality-adjusted years, costs. performed sensitivity scenario analyses uncertainty results. Results—Admission resulted gain 0.22 years (95% credible range [CR], 0.12–0.33) a...