Expression of Ep-CAM in cervical squamous epithelia correlates with an increased proliferation and the disappearance of markers for terminal differentiation.

作者: S. O. Warnaar , C. M. Van Rhijn , W. Van Driel , S. V. Litvinov , H. A. M. Bakker

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摘要: … However, we have demonstrated that Ep-CAM is of importance for intercellular interactions of carcinoma cells that have decreased levels of cadherins,3 which suggests that Ep-CAM is …

参考文章(14)
J. A. DiPaolo, Paul Edward Bowden, C. D. Woodworth, J. Doniger, W. D. Lancaster, L. Pirisi, W. Barnes, Characterization of normal human exocervical epithelial cells immortalized in vitro by Papillomavirus types 16 and 18 DNA Cancer Research. ,vol. 48, pp. 4620- 4628 ,(1988)
I. Leigh, M. Pruszczynski, B. Lane, F. Ramaekers, S. Troyanovsky, C. Schijf, P. Vooijs, M. Link, F. Smedts, Keratin expression in cervical cancer American Journal of Pathology. ,vol. 141, pp. 497- 511 ,(1992)
K. Tsutsumi, K. Kikuchi, A. Pater, M. M. Pater, S. Yasumoto, Y. Ohta, Qi Sun, In vitro and in vivo analysis of cellular origin of cervical squamous metaplasia. American Journal of Pathology. ,vol. 143, pp. 1150- 1158 ,(1993)
Fiona M. Watt, Involucrin and Other Markers of Keratinocyte Terminal Differentiation Journal of Investigative Dermatology. ,vol. 81, pp. S100- S103 ,(1983) , 10.1111/1523-1747.EP12540786
D. E. Hughes, G. Rebello, A. Al-Nafussi, Integrin expression in squamous neoplasia of the cervix The Journal of Pathology. ,vol. 173, pp. 97- 104 ,(1994) , 10.1002/PATH.1711730205
O. Tellechea, J. P. Reis, J. C. Domingues, A. Poiares Baptista, Monoclonal antibody Ber EP4 distinguishes basal-cell carcinoma from squamous-cell carcinoma of the skin. American Journal of Dermatopathology. ,vol. 15, pp. 452- 455 ,(1993) , 10.1097/00000372-199310000-00007
A. Tsubura, H. Senzaki, M. Sasaki, J. Hilgers, S. Morii, Immunohistochemical demonstration of breast-derived and/or carcinoma-associated glycoproteins in normal skin appendages and their tumors. Journal of Cutaneous Pathology. ,vol. 19, pp. 73- 79 ,(1992) , 10.1111/J.1600-0560.1992.TB01562.X
S V Litvinov, M P Velders, H A Bakker, G J Fleuren, S O Warnaar, Ep-CAM : a human epithelial antigen is a homophilic cell-cell adhesion molecule Journal of Cell Biology. ,vol. 125, pp. 437- 446 ,(1994) , 10.1083/JCB.125.2.437