Snake Venom Detection Kit (SVDK): Update on Current Aspects and Challenges

摘要: Snakebite is a medical emergency causing considerable morbidity and mortality worldwide, particularly in the tropics. Snake venom components are known to vary greatly leading varied clinical manifestations following snakebite. The success of antivenom therapy, which mainstay usually depends on snake species involved, uncertainties concerning involved remain major hurdle effective management Therefore, proper identification prime importance, consequently development SnakeVenomDiagnostic Kit(SVDK).Over theyears, variousdetectionstestshavebeendeveloped, with immunological-reaction-based enzyme-linked immunosorbent assay (ELISA) method being most widely used. However, recent times various other techniques, such as optical immunoassays (OIA), venom/antibody microarray assay, PCR based assays, etc., also developed much more promise real-time applications. Furthermore, tests tend be highly species-specific, reliable, sensitive, rapid, inexpensive, stable, simple, portable for field use. It desirable that each country develops optimizes its own regional species-specific diagnosis kits Considering doubts commercial viability developing SVDK, public/private partnerships have nurtured. This work attempts summarize existing techniques detection current use, especially their advantages disadvantages. focuses developments discusses present challenges application SVDK successful usage future.