Hyperadiponectinemia in newborns: Relationship with leptin levels and birth weight

摘要: Objective: Adiponectin is the only adipose-specific hormone that, despite its exclusive production by adipose tissue, reduced in obesity and inversely correlated with leptin levels adults. The aim of this study was to evaluate adiponectin concentration umbilical cord blood at different gestational ages investigate possible associations birth weight. Research Methods Procedures: Umbilical obtained from 132 newborns (male = 65, female 67, age: 35 42 weeks). anthropometric variables studied were weight, length, body weight/body ponderal index. Adiponectin, insulin, measured radioimmunoassay methods. Results: males not those females (24.10 ± 0.81 vs. 25.62 0.84 μg/mL, p 0.280). concentrations positively weight (p < 0.05), length age 0.01), 0.01). Discussion: These findings indicate that present after weeks gestation, higher than usually found adults, no gender differences, a positive correlation leptin. results suggest could neonatal hyperadiponectinemia be associated increase fetal tissue but also reduction an unknown mechanism related suppression observed