Interventions psychothérapeutiques et psychosociales et endophénotypes dans les troubles bipolaires

作者: N. Correard , S.N. Elissalde , J.-M. Azorin , R. Belzeaux , E. Fakra

DOI: 10.1016/S0013-7006(12)70088-X

关键词:

摘要: Resume Maladies a determinisme complexe, les troubles bipolaires, impliquent la fois des facteurs de vulnerabilite environnementale et genetique. La caracterisation ces vulnerabilites permettrait d’une part, une meilleure connaissance leur etiologie d’autre d’envisager le developpement nouvelles therapeutiques, plus specialisees, voire preventives. recherche en psychiatrie genetique permis mettre evidence endophenotypes candidats associes aux bipolaires. Ce sont « traits » cliniques ou biologiques dits endogenes, simples, biologiquement elementaires que phenotypes lies directement consequences physiologiques genes leurs polymorphismes. Cibler certains d’entre eux avec interventions psychotherapeutiques psychosociales adaptees, pourrait reduire liees expression ainsi avoir action sur l’evolution maladie mais aussi preventive.

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