Application of In Vitro Technologies for Production of Vasicine and Vasicinone: Key Bioactive Compounds of Adhatoda spp.

作者: Saikat Gantait , Monisha Mitra , Jitendriya Panigrahi

DOI: 10.1007/978-981-15-1761-7_4

关键词:

摘要: Adhatoda vasica or Malabar nut belongs to the family, Acanthaceae. The other well-known members of this genus are A. zeylanica, beddomei, etc. These evergreen and perennial shrub exhibiting high pharmaceutical value. plant consists a wide array metabolites that are, namely, vasicine, vasicinone, vasicinol, vasicine glycoside, 5-hydroxy deoxy adhavasicinone, vasicolinone, adhatodine, vasnetine anisotine. leaves roots exhibit anti-inflammatory antiseptic properties, respectively. Having immense potential for its use in industry, these species need be harnessed through biotechnological advancements enhanced production their secondary metabolites. This chapter provides an insight approaches, mainly vitro-based methods via direct indirect regeneration (callus-mediated) cell suspension culture, boosted with elicitors, enhancing accumulation key (vasicine vasicinone). Additionally, loopholes existing technologies arenas not yet explored also addressed needs worked on near future.

参考文章(47)
B J Ghatak, O P Gupta, M L Sharma, C K Atal, Pharmacological investigations of vasicine and vasicinone--the alkaloids of Adhatoda vasica. Indian Journal of Medical Research. ,vol. 66, pp. 680- 691 ,(1977)
Gauri Abhyankar, VD Reddy, None, Rapid micropropagation via axillary bud proliferation of Adhatoda vasica Nees from nodal segments. Indian Journal of Experimental Biology. ,vol. 45, pp. 268- 271 ,(2007)
KadamShalaka Dinesh, Sandhya Parameswaran, Micropropogation and Organogenesis in Adhatoda vasika For The Estimation Of Vascine Pharmacognosy Magazine. ,vol. 5, pp. 359- 363 ,(2009) , 10.4103/0973-1296.58567
Balawant S. Joshi, M.Gary Newton, Doo Won Lee, Angela D. Barber, S.William Pelletier, Reversal of absolute stereochemistry of the pyrrolo[2,1-b]quinazoline alkaloids vasicine, vasicinone, vasicinol and vasicinolone Tetrahedron-asymmetry. ,vol. 7, pp. 25- 28 ,(1996) , 10.1016/0957-4166(95)00412-2
Shamsul Hayat, Qaiser Hayat, Mohammed Nasser Alyemeni, Arif Shafi Wani, John Pichtel, Aqil Ahmad, Role of proline under changing environments: A review Plant Signaling & Behavior. ,vol. 7, pp. 1456- 1466 ,(2012) , 10.4161/PSB.21949
Wayne H. Loescher, R. Huw Tyson, John D. Everard, Robert J. Redgwell, Roderick L. Bieleski, Mannitol Synthesis in Higher Plants : Evidence for the Role and Characterization of a NADPH-Dependent Mannose 6-Phosphate Reductase. Plant Physiology. ,vol. 98, pp. 1396- 1402 ,(1992) , 10.1104/PP.98.4.1396
Hong Gao, Yi-Na Huang, Bo Gao, Peng Li, Chika Inagaki, Jun Kawabata, Inhibitory effect on α-glucosidase by Adhatoda vasica Nees Food Chemistry. ,vol. 108, pp. 965- 972 ,(2008) , 10.1016/J.FOODCHEM.2007.12.002