Metastases to Bone

摘要: Over 100,000 patients per year in the United States have newly recognized metastases to bone [1]. Usually primary tumor has been identified, but occasionally a metastasis will be first clinical indication of cancer. These lesions may major source pain, neurologic deficit, and hypercalcemia compromise skeletal integrity with potentially disastrous results weight-bearing bone. The most frequent sources are cancers breast, prostate, lung [2, 3]. Metastases from other sites, including kidney, thyroid, endometrium, cervix, bladder, gastrointestinal tract account for less than 20% known [4]. Although ultimate prognosis is poor, many patients, particularly those survive months or even years. Consequently, nearly all need treatment relieve symptoms signs caused by cancer remainder their lives.