The nasal methylome as a biomarker of asthma and airway inflammation in children.

作者: Liming Liang , Brent A. Coull , Marie-France Hivert , Peggy S. Lai , Erick Forno

DOI: 10.1038/S41467-019-11058-3

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摘要: The nasal cellular epigenome may serve as biomarker of airway disease and environmental response. Here we collect nasal swabs from the anterior nares of 547 children (mean-age …

参考文章(54)
Cheng-Jian Xu, Cilla Söderhäll, Mariona Bustamante, Nour Baïz, Olena Gruzieva, Ulrike Gehring, Dan Mason, Leda Chatzi, Mikel Basterrechea, Sabrina Llop, Maties Torrent, Francesco Forastiere, Maria Pia Fantini, Karin C Lødrup Carlsen, Tari Haahtela, Andréanne Morin, Marjan Kerkhof, Simon Kebede Merid, Bianca van Rijkom, Soesma A Jankipersadsing, Marc Jan Bonder, Stephane Ballereau, Cornelis J Vermeulen, Raul Aguirre-Gamboa, Johan C de Jongste, Henriette A Smit, Ashish Kumar, Göran Pershagen, Stefano Guerra, Judith Garcia-Aymerich, Dario Greco, Lovisa Reinius, Rosemary R C McEachan, Raf Azad, Vegard Hovland, Petter Mowinckel, Harri Alenius, Nanna Fyhrquist, Nathanaël Lemonnier, Johann Pellet, Charles Auffray, Pieter van der Vlies, Cleo C van Diemen, Yang Li, Cisca Wijmenga, Mihai G Netea, Miriam F Moffatt, William O C M Cookson, Josep M Anto, Jean Bousquet, Tiina Laatikainen, Catherine Laprise, Kai-Håkon Carlsen, Davide Gori, Daniela Porta, Carmen Iñiguez, Jose Ramon Bilbao, Manolis Kogevinas, John Wright, Bert Brunekreef, Juha Kere, Martijn C Nawijn, Isabella Annesi-Maesano, Jordi Sunyer, Erik Melén, Gerard H Koppelman, DNA methylation in childhood asthma: an epigenome-wide meta-analysis The Lancet Respiratory Medicine. ,vol. 6, pp. 379- 388 ,(2018) , 10.1016/S2213-2600(18)30052-3
Andrew P. Feinberg, The Key Role of Epigenetics in Human Disease Prevention and Mitigation The New England Journal of Medicine. ,vol. 378, pp. 1323- 1334 ,(2018) , 10.1056/NEJMRA1402513
Steve Horvath, Kenneth Raj, DNA methylation-based biomarkers and the epigenetic clock theory of ageing. Nature Reviews Genetics. ,vol. 19, pp. 371- 384 ,(2018) , 10.1038/S41576-018-0004-3
Cheng Peng, Andres Cardenas, Sheryl L. Rifas-Shiman, Marie-France Hivert, Diane R. Gold, Thomas A. Platts-Mills, Xihong Lin, Emily Oken, Andrea A. Baccarelli, Augusto A. Litonjua, Dawn L. DeMeo, Epigenome-wide association study of total serum immunoglobulin E in children: a life course approach. Clinical Epigenetics. ,vol. 10, pp. 1- 14 ,(2018) , 10.1186/S13148-018-0488-X
Erick Forno, Ting Wang, Cancan Qi, Qi Yan, Cheng-Jian Xu, Nadia Boutaoui, Yueh-Ying Han, Daniel E Weeks, Yale Jiang, Franziska Rosser, Judith M Vonk, Sharon Brouwer, Edna Acosta-Perez, Angel Colón-Semidey, María Alvarez, Glorisa Canino, Gerard H Koppelman, Wei Chen, Juan C Celedón, DNA methylation in nasal epithelium, atopy, and atopic asthma in children: a genome-wide study. The Lancet Respiratory Medicine. ,vol. 7, pp. 336- 346 ,(2019) , 10.1016/S2213-2600(18)30466-1
Cheng Peng, Andres Cardenas, Sheryl L. Rifas-Shiman, Marie-France Hivert, Diane R. Gold, Thomas A. Platts-Mills, Xihong Lin, Emily Oken, Lydiana Avila, Juan C. Celedón, Scott T. Weiss, Andrea A. Baccarelli, Augusto A. Litonjua, Dawn L. DeMeo, Epigenetic age acceleration is associated with allergy and asthma in children in Project Viva. The Journal of Allergy and Clinical Immunology. ,vol. 143, pp. 2263- ,(2019) , 10.1016/J.JACI.2019.01.034
Zongli Xu, Liang Niu, Leping Li, Jack A. Taylor, ENmix: a novel background correction method for Illumina HumanMethylation450 BeadChip. Nucleic Acids Research. ,vol. 44, ,(2016) , 10.1093/NAR/GKV907
M. W. H. Pijnenburg, J. C. De Jongste, Exhaled nitric oxide in childhood asthma: a review Clinical & Experimental Allergy. ,vol. 38, pp. 246- 259 ,(2007) , 10.1111/J.1365-2222.2007.02897.X
Randy L. Jirtle, Michael K. Skinner, Environmental epigenomics and disease susceptibility Nature Reviews Genetics. ,vol. 8, pp. 253- 262 ,(2007) , 10.1038/NRG2045
Noriko Kitamura, Akio Mori, Hideki Tatsumi, Soichi Nemoto, Takachika Hiroi, Osamu Kaminuma, Zinc finger protein, multitype 1, suppresses human Th2 development via downregulation of IL-4. International Archives of Allergy and Immunology. ,vol. 155, pp. 53- 56 ,(2011) , 10.1159/000327292