Impact of Activated Vitamin D and Race on Survival among Hemodialysis Patients

摘要: Contrary to most examples of disparities in health outcomes, black patients have improved survival compared with white after initiating hemodialysis. Understanding potential explanations for this observation may important clinical implications minorities general. This study tested the hypothesis that greater use activated vitamin D therapy accounts advantage observed and Hispanic on In a prospective cohort non-Hispanic (n = 5110), 979), 3214) incident hemodialysis patients, higher parathyroid hormone levels at baseline were primary determinant prescribing therapy. Median was highest among who likely receive dosage. One-year mortality lower (16 16 versus 23%; P < 0.01), but there significant interaction between race ethnicity, therapy, survival. multivariable analyses treated D, had 16% difference lost when adjusted contrast, untreated 35% an association persisted several sensitivity analyses. conclusion, be one explanation racial differences patients. Further studies should determine whether treatment based biologic contribute other conditions.