MRI Detection of Intratumoral Fat in Hepatocellular Carcinoma: Potential Biomarker for a More Favorable Prognosis
作者： Surachate Siripongsakun , Jeong K. Lee , Steven S. Raman , Myron J. Tong , James Sayre
DOI: 10.2214/AJR.12.8632
关键词:
摘要: OBJECTIVE. The purpose of this study was to determine whether the presence intratumoral fat in hepatocellular carcinoma (HCC) could serve as an imaging biomarker predict a favorable prognosis. MATERIALS AND METHODS. After search radiology and pathology databases from January 2002 December 2010, cohort patients with fat-containing HCC imaged by chemical-shift MRI techniques matched nonfat-containing for TNM stage type subsequent treatment. number tumor progression, time progression (TTP), overall survival (OS) were determined each cohort. RESULTS. There 46 included Tumor more prevalent non-fat-containing (30 patients, 65.2%) compared (16 34.7%; p = 0.001). Distant metastasis occurred commonly (10 patient, 21.7%) (t...
sci-hub.se 参考文章(17)
J Martín, M Sentís, A Zidan, L Donoso, J Puig, J Falcó, R Bella, Fatty metamorphosis of hepatocellular carcinoma: detection with chemical shift gradient-echo MR imaging. Radiology. ,vol. 195, pp. 125- 130 ,(1995) , 10.1148/RADIOLOGY.195.1.7892452
Myron J. Tong, Hai-En Sun, Carlos Hsien, David S. K. Lu, Surveillance for hepatocellular carcinoma improves survival in Asian-American patients with hepatitis B: results from a community-based clinic. Digestive Diseases and Sciences. ,vol. 55, pp. 826- 835 ,(2010) , 10.1007/S10620-009-1059-Y
Hollins P. Clark, W. Forrest Carson, Peter V. Kavanagh, Coty P. H. Ho, Perry Shen, Ronald J. Zagoria, Staging and current treatment of hepatocellular carcinoma. Radiographics. ,vol. 25, ,(2005) , 10.1148/RG.25SI055507
Riccardo Lencioni, Josep Llovet, Modified RECIST (mRECIST) Assessment for Hepatocellular Carcinoma Seminars in Liver Disease. ,vol. 30, pp. 52- 60 ,(2010) , 10.1055/S-0030-1247132
Kazuhiro Kondo, Kazuo Chijiiwa, Mayumi Funagayama, Masahiro Kai, Kazuhiro Otani, Jiro Ohuchida, Differences in long-term outcome and prognostic factors according to viral status in patients with hepatocellular carcinoma treated by surgery. Journal of Gastrointestinal Surgery. ,vol. 12, pp. 468- 476 ,(2008) , 10.1007/S11605-007-0402-X
Wei-Yu Kao, Chien-Wei Su, Gar-Yang Chau, Wing-Yiu Lui, Chew-Wun Wu, Jaw-Ching Wu, A comparison of prognosis between patients with hepatitis B and C virus-related hepatocellular carcinoma undergoing resection surgery. World Journal of Surgery. ,vol. 35, pp. 858- 867 ,(2011) , 10.1007/S00268-010-0928-Z
Kyung Won Kim, Jeong Min Lee, Byung Ihn Choi, Assessment of the treatment response of HCC. Abdominal Imaging. ,vol. 36, pp. 300- 314 ,(2011) , 10.1007/S00261-011-9683-3
Qiang Li, Huikai Li, Yu Qin, P Peter Wang, Xishan Hao, None, Comparison of surgical outcomes for small hepatocellular carcinoma in patients with hepatitis B versus hepatitis C: a Chinese experience. Journal of Gastroenterology and Hepatology. ,vol. 22, pp. 1936- 1941 ,(2007) , 10.1111/J.1440-1746.2006.04619.X
E.D. Saad, A. Katz, Progression-free survival and time to progression as primary end points in advanced breast cancer: often used, sometimes loosely defined Annals of Oncology. ,vol. 20, pp. 460- 464 ,(2008) , 10.1093/ANNONC/MDN670
J.E. Dancey, L.E. Dodd, R. Ford, R. Kaplan, M. Mooney, L. Rubinstein, L.H. Schwartz, L. Shankar, P. Therasse, Recommendations for the assessment of progression in randomised cancer treatment trials European Journal of Cancer. ,vol. 45, pp. 281- 289 ,(2009) , 10.1016/J.EJCA.2008.10.042