Pax3 and Pax7 expression and regulation in the avian embryo

摘要: Satellite cells are essential for postnatal growth and repair of skeletal muscle. The paired-box transcription factors Pax3 Pax7 expressed in emerging muscle precursors. Recent studies have traced the origin satellite to embryonic dermomyotome, however, their developmental regulation throughout embryogenesis remains unclear. We show overlying surface ectoderm lateral plate expression, that neural tube necessary expression within dorsal somite. Furthermore we notochord acts down regulate both genes. Moreover, identify diffusible these tissues act maintain Pax3+ Pax7+ Wnt1, 3a, 4 6 proteins able up expand Finally, Wnt6 can mimic effect expression.