Healthcare resource use and medical costs for the management of oesophageal cancer

作者: Simon Eckermann , David Watson , George Mayne , P Fahey , NG Hirst

DOI: 10.1002/BJS.7599

关键词:

摘要: Background: This study examined the interaction between natural history, current practice patterns in diagnosis, monitoring and treatment of oesophageal cancer, associated health resource utilization costs. Methods: A cost analysis a prospective population-based cohort 1100 patients with primary diagnosis cancer was performed using chart review from Australian Cancer Study Clinical Follow-Up Study. The enabled estimation healthcare resources costs 2009 euros by stage disease pathway. Results: Most (88·5 per cent) presented II, III or IV cancer; 61·1 cent (672 1100) were treated surgically. Overall mean €37 195 (median €29 114) for undergoing surgery €17 281 €13 066) those without surgery. Surgery contributed 66·4 total (mean €24 697 patient) surgical group. In non-surgical group, use chemotherapy more prevalent (81·9 patients) Other important determinants gastro-oesophageal junction tumours, location tumour stage. Mean monitored Barrett's oesophagus (7·3 lower, although about one-third still advanced-stage cancer. Conclusion: managing high dominated surgically Radiotherapy, subtype also important. Monitoring earlier-stage detection lower management costs, but potential net benefit surveillance strategies needs further investigation.

参考文章(25)
Narissa J. Nonzee, Karen A. Fitzner, June M. McKoy, Cara C. Tigue, Charles L. Bennett, Beatrice J. Edwards, Motasem Alkhatib, Carlos R. Bolden, Cost considerations in the management of cancer in the older patient. Oncology. ,vol. 21, pp. 851- 857 ,(2007)
Efty P Stavrou, Heather J McElroy, Deborah F Baker, Garett Smith, James F Bishop, Adenocarcinoma of the oesophagus: incidence and survival rates in New South Wales, 1972-2005. The Medical Journal of Australia. ,vol. 191, pp. 310- 314 ,(2009) , 10.5694/J.1326-5377.2009.TB02813.X
Andrew M. Jones, Models for Health Care Oxford Handbooks Online. ,(2011) , 10.1093/OXFORDHB/9780195398649.013.0024
Nicholas G Hirst, Louisa G Gordon, David C Whiteman, David I Watson, Jan J Barendregt, None, Is endoscopic surveillance for non-dysplastic Barrett's esophagus cost-effective? Review of economic evaluations Journal of Gastroenterology and Hepatology. ,vol. 26, pp. 247- 254 ,(2011) , 10.1111/J.1440-1746.2010.06506.X
A. Soni, A. Sonnenberg, Healthcare resource utilization in the management of oesophageal adenocarcinoma Alimentary Pharmacology & Therapeutics. ,vol. 15, pp. 945- 951 ,(2001) , 10.1046/J.1365-2036.2001.01004.X
Andrew Briggs, Taane Clark, Jane Wolstenholme, Philip Clarke, Missing... presumed at random: cost-analysis of incomplete data. Health Economics. ,vol. 12, pp. 377- 392 ,(2003) , 10.1002/HEC.766
Jalpa A. Doshi, Henry A. Glick, Daniel Polsky, Analyses of Cost Data in Economic Evaluations Conducted Alongside Randomized Controlled Trials Value in Health. ,vol. 9, pp. 334- 340 ,(2006) , 10.1111/J.1524-4733.2006.00122.X
Ya-Chen Tina Shih, Michael T. Halpern, Economic evaluations of medical care interventions for cancer patients: how, why, and what does it mean? CA: A Cancer Journal for Clinicians. ,vol. 58, pp. 231- 244 ,(2008) , 10.3322/CA.2008.0008
Simon Eckermann, Michael Coory, Andrew R. Willan, Consistently Estimating Absolute Risk Difference when Translating Evidence to Jurisdictions of Interest PharmacoEconomics. ,vol. 29, pp. 87- 96 ,(2011) , 10.2165/11585910-000000000-00000