Annexin A2 contributes to lung injury and fibrosis by augmenting factor Xa fibrogenic activity

作者: Michael Schuliga , Jade Jaffar , Asres Berhan , Shenna Langenbach , Trudi Harris

DOI: 10.1152/AJPLUNG.00553.2016

关键词:

摘要: In lung injury and disease, including idiopathic pulmonary fibrosis (IPF), extravascular factor X is converted into Xa (FXa), a coagulant protease with fibrogenic actions. Extracellular anne...

参考文章(62)
Shenna Y. Langenbach, Ben J. Wheaton, Darren J. Fernandes, Catherine Jones, Tara E. Sutherland, Bronwyn C. Wraith, Trudi Harris, Michael J. Schuliga, Catriona McLean, Alastair G. Stewart, Resistance of fibrogenic responses to glucocorticoid and 2-methoxyestradiol in bleomycin-induced lung fibrosis in miceThis article is one of a selection of papers published in the Special Issue on Recent Advances in Asthma Research. Canadian Journal of Physiology and Pharmacology. ,vol. 85, pp. 727- 738 ,(2007) , 10.1139/Y07-065
Mitchell A. Olman, Kimberly E. White, Lorraine B. Ware, Warren L. Simmons, Etty N. Benveniste, Sha Zhu, Jerome Pugin, Michael A. Matthay, Pulmonary Edema Fluid from Patients with Early Lung Injury Stimulates Fibroblast Proliferation through IL-1β-Induced IL-6 Expression Journal of Immunology. ,vol. 172, pp. 2668- 2677 ,(2004) , 10.4049/JIMMUNOL.172.4.2668
A G Stewart, Y C Xia, T Harris, S Royce, J A Hamilton, M Schuliga, Plasminogen-stimulated airway smooth muscle cell proliferation is mediated by urokinase and annexin A2, involving plasmin-activated cell signalling. British Journal of Pharmacology. ,vol. 170, pp. 1421- 1435 ,(2013) , 10.1111/BPH.12422
Michael Schuliga, Simon G. Royce, Shenna Langenbach, Asres Berhan, Trudi Harris, Christine R. Keenan, Alastair G. Stewart, The Coagulant Factor Xa Induces Protease-Activated Receptor-1 and Annexin A2-Dependent Airway Smooth Muscle Cytokine Production and Cell Proliferation. American Journal of Respiratory Cell and Molecular Biology. ,vol. 54, pp. 200- 209 ,(2016) , 10.1165/RCMB.2014-0419OC
Georgia Schäfer, Jessica K. Hitchcock, Tamlyn M. Shaw, Arieh A. Katz, M. Iqbal Parker, A Novel Role of Annexin A2 in Human Type I Collagen Gene Expression Journal of Cellular Biochemistry. ,vol. 116, pp. 408- 417 ,(2015) , 10.1002/JCB.24989
Gabriela Cesarman-Maus, Carlos Cantú-Brito, Fernando Barinagarrementeria, Rosario Villa, Elba Reyes, Jorge Sanchez-Guerrero, Katherine A. Hajjar, Ethel Garcia Latorre, Autoantibodies Against the Fibrinolytic Receptor, Annexin A2, in Cerebral Venous Thrombosis Stroke. ,vol. 42, pp. 501- 503 ,(2011) , 10.1161/STROKEAHA.110.592121
Yi‐Ting Fang, Chiou‐Feng Lin, Chi‐Yun Wang, Robert Anderson, Yee‐Shin Lin, None, Interferon‐γ stimulates p11‐dependent surface expression of annexin A2 in lung epithelial cells to enhance phagocytosis Journal of Cellular Physiology. ,vol. 227, pp. 2775- 2787 ,(2012) , 10.1002/JCP.23026
Jochen Frenzel, Christian Gessner, Torsten Sandvoss, Stefan Hammerschmidt, Wolfgang Schellenberger, Ulrich Sack, Klaus Eschrich, Hubert Wirtz, Outcome Prediction in Pneumonia Induced ALI/ARDS by Clinical Features and Peptide Patterns of BALF Determined by Mass Spectrometry PLoS ONE. ,vol. 6, pp. e25544- ,(2011) , 10.1371/JOURNAL.PONE.0025544
H. TAKIZAWA, M. SATOH, H. OKAZAKI, G. MATSUZAKI, N. SUZUKI, A. ISHII, M. SUKO, H. OKUDAIRA, Y. MORITA, K. ITO, Increased IL‐6 and IL‐8 in bronchoalveolar lavage fluids (BALF) from patients with sarcoidosis: correlation with the clinical parameters Clinical and Experimental Immunology. ,vol. 107, pp. 175- 181 ,(1997) , 10.1046/J.1365-2249.1997.D01-905.X
Tomoyuki Tanaka, Shinya Akatsuka, Munetaka Ozeki, Tomoyuki Shirase, Hiroshi Hiai, Shinya Toyokuni, Redox regulation of annexin 2 and its implications for oxidative stress-induced renal carcinogenesis and metastasis. Oncogene. ,vol. 23, pp. 3980- 3989 ,(2004) , 10.1038/SJ.ONC.1207555