Clinical and inflammatory features of occupational asthma caused by persulphate salts in comparison with asthma associated with occupational rhinitis.

摘要: To cite this article: Moscato G, Pala Perfetti L, Frascaroli M, Pignatti P. Clinical and inflammatory features of occupational asthma caused by persulphate salts in comparison with associated rhinitis. Allergy 2010; 65: 784–790. Abstract Background:  The relationships between rhinitis are still a crucial point respiratory allergy have scarcely been analysed setting. We aimed to compare the clinical subjects only (OA) OA (OAR) salts. Methods:  charts 26 diagnosed our Unit as ammonium (AP), confirmed specific inhalation challenge (SIC), were reviewed. Twenty-two out twenty-six patients underwent pre-SIC-induced sputum test (IS) 24/26 nasal secretion collection processing. Results:  Twelve received diagnosis OA-only 14/26 OAR. Duration exposure before diagnosis, latency period beginning symptom onset, basal FEV1, airway reactivity methacholine severity did not differ two groups. Eosinophilic inflammation upper lower airways characterized both Eosinophil percentage IS tended be higher OAR [11.9 (5.575–13.925)%] than [2.95 (0.225–12.5)%] (P = 0.31). Eosinophilia secretions was present [55 (46–71)%] [38 (15–73.5)%], without any significant difference. Discussion:  Our results indicate that because coexists half patients. Unexpectedly, seem an impact on natural history asthma. finding manifestations supports united disease concept result persulphates.