A General and Convenient Catalytic Synthesis of Nitriles from Amides and Silanes
作者： Shaolin Zhou , Kathrin Junge , Daniele Addis , Shoubhik Das , Matthias Beller
DOI: 10.1021/OL900716Q
关键词:
摘要: A new and convenient protocol for the catalytic dehydration of aromatic aliphatic amides using silanes in presence amounts fluoride is presented. The synthesis nitriles proceeds with high selectivity under mild conditions. Notably, a wide substrate range converted good to excellent yields.
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