Mukaiyama’s reagent promoted mild protocol for one-pot metal-free synthesis of dihydro quinazolinones
作者： Chatrasal S. Rajput , Shweta Srivastava , Ashish Kumar , Arunendra Pathak
DOI: 10.1016/J.TETLET.2020.152791
关键词:
摘要: Abstract We have developed a fast and convenient method to prepare dihydroquinazolin-4(1H)-ones from anthranilamide different aromatic aldehydes by using the Mukaiyama reagent. The reactions proceeded smoothly with broad scope of substrates providing expected products in good excellent yields under low environmental factor high atom economy. metal-free condition ease product isolation are highlighted advantages solving issue trace metal contamination synthesized pharmaceuticals.
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