Wet, volatile, and dry biomarkers of exercise-induced muscle fatigue.

摘要: The physiological background of exercise-induced muscle fatigue(EIMUF) is only poorly understood. Thus, monitoring EIMUF by a single or multiple biomarkers(BMs) under debate. After systematic literature review 91 papers were included. mainly due to depletion substrates, increased oxidative stress, membrane depolarisation following potassium depletion, hyperthermia, damage, impaired oxygen supply the muscle, activation an inflammatory response, calcium-handling. Dehydration, hyperammonemia, mitochondrial biogenesis, and genetic responses are also discussed. Since dependent on age, sex, degree fatigue, type, intensity, duration exercise, energy during climate, training status (physical fitness), health status, BMs currently available for have limited reliability. Generally, wet, volatile, dry differentiated. Among most promising include power output measures, electrophysiological cardiologic questionnaires. wet those applicable markers ATP-metabolism, inflammation. VO2-kinetics used as volatile BM. Though physiology remains be fully elucidated, some been recently introduced, which together with other BMs, could useful in EIMUF. combination biomarkers seems more efficient than biomarker monitor However, it essential that efficacy, reliability, applicability each BM candidate validated appropriate studies.