作者: Stefania Zampatti , Raffaella Cascella , Michele Ragazzo , Claudia Strafella , Carlo Caltagirone
DOI: 10.3390/JPM11030213
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摘要: Human behaviour is determined by a complex interaction of genetic and environmental factors. Several studies have demonstrated different associations between human numerous variants. In particular, allelic variants in SLC6A4, MAOA, DRD4, DRD2 showed statistical with major depressive disorder, antisocial behaviour, schizophrenia, bipolar disorder; BDNF polymorphic were associated depressive, bipolar, schizophrenia diseases, TPH2 found both people unipolar depression children attention deficit-hyperactivity disorder (ADHD). Independent failed to confirm criminal aggressive behaviour. the present study, set involved serotoninergic, dopaminergic, neurobiological pathways selected from those previously The distribution these was compared across worldwide populations. While data on single differential populations, differences be significant when comprehensive analysis conducted total number published lack reproducibility association date, weakness associations, heterogeneity phenotype, massive influence environment do not allow us consider as undoubtedly Moreover, absence ethnic predisposition