Screening β-arrestin recruitment for the identification of natural ligands for orphan G-protein-coupled receptors.

作者: Andrew Green , Mark J. Wigglesworth , Steve Rees , Craig Southern , Jennifer M. Cook

DOI: 10.1177/1087057113475480

关键词:

摘要: … β-Arrestin recruitment represents a robust GPCR screening technology, and ligand-biased signaling is emerging as a therapeutically exploitable feature of GPCR biology. The …

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