Hohenheim consensus workshop: copper.

摘要: Copper (Cu) is an essential trace element with many physiological functions. Homeostatic mechanisms exist to allow Cu act as a cofactor in enzymatic processes and prevent accumulation of toxic levels. The aim this commentary better understand the role dietary supply deficiency under pathological conditions. essentiality can be attributed its number enzymes that are involved defence against oxidative stress. Cu, however, has second face, compound it observed accumulating evidence hepatic, neurodegenerative cardiovascular diseases. destructive potential inherent physico-chemical properties. main property ability take part Fenton-like reactions which highly reactive extremely deleterious hydroxyl radical formed. Diseases caused by overload could based on genetic predisposition. Thus, assessment risk-groups, such infants impaired homeostasis regarding detoxification, special interest, their intake resuspended formula milk may very high. This implies need for reliable diagnostic markers determine status. These topics were introduced at workshop participants followed extensive group discussion. consensus statements agreed all members. One conclusions re-assessment published data necessary future research required.